Adesam 400mg Tablet (Ursodeoxycholic Acid) – Treatment for Liver Disease & Cholestasis

Adesam 400mg Tablet is a hepatoprotective medication prescribed for treating liver disorders, particularly intrahepatic cholestasis – a condition characterized by impaired bile flow. This high-dose formulation provides enhanced therapeutic benefits for patients requiring stronger treatment. The tablet works by protecting liver cells from toxic damage while promoting normal bile production and flow. Suitable for long-term therapy, Adesam 400mg helps maintain liver function and may prevent disease progression. While generally well-tolerated, some patients may experience mild digestive disturbances that typically resolve with continued use.

Uses of Adesam 400mg Tablet:

• Primary treatment for intrahepatic cholestasis
• Management of chronic liver diseases
• Protection against hepatotoxic damage
• Improvement of bile flow in biliary disorders

Benefits of Adesam 400mg Tablet:

Therapeutic advantages include:

• Enhanced potency with 400mg formulation
• Protects and regenerates liver cells
• Improves bile composition and flow
• Reduces liver enzyme levels
• May slow disease progression in certain conditions

Side Effects of Adesam 400mg Tablet:

Common but typically mild effects:

• Nausea
• Diarrhea
• Abdominal discomfort
• Constipation
• Dizziness

Consult your doctor if persistent or severe.

How to Use Adesam 400mg Tablet?

• Take exactly as prescribed by your hepatologist
• Swallow whole with water – do not crush or chew
• May take with or without food
• Maintain consistent dosing schedule
• Regular liver function tests recommended

How Adesam 400mg Tablet Works?

Pharmacological action:

• Contains ursodeoxycholic acid as active ingredient
• Replaces toxic bile acids with non-toxic forms
• Stimulates hepatobiliary secretion
• Exerts cytoprotective effects on hepatocytes
• Reduces cholesterol saturation in bile

Safety Advice:

• Alcohol: Strictly avoid – may worsen liver damage
• Pregnancy: Use only if clearly needed after medical consultation
• Breastfeeding: Safety not established – consult physician
• Driving: Caution advised due to potential dizziness
• Kidney Disease: Requires medical supervision
• Liver Disease: Regular monitoring essential

What If You Miss a Dose?

Take as soon as remembered unless close to next dose time. Never take double dose.

FAQs:

Q1. How does Adesam 400mg differ from lower doses?

The 400mg formulation provides higher concentration for patients requiring stronger therapy, potentially reducing tablet burden for those needing high doses.

Q2. Can Adesam reverse liver damage?

While it can’t reverse existing cirrhosis, it may help prevent further damage and improve liver function in certain conditions when used early.

Q3. Are there any dietary restrictions?

Maintain balanced nutrition with emphasis on lean proteins and vegetables. Limit saturated fats and avoid alcohol completely.

Q4. How long until I see improvement?

Liver enzyme improvements may appear within 4-8 weeks, but full benefits often require 3-6 months of continuous therapy.

Q5. Can I take other liver supplements?

Consult your doctor before combining with other hepatics as interactions may occur.

Q6. Does it help with itching from cholestasis?

Yes, by improving bile flow it often reduces pruritus associated with cholestatic conditions.

Q7. What monitoring is required?

Regular LFTs, bilirubin, and bile acid tests help assess treatment response and guide duration.