Adcapone Tablet – Entacapone | Treatment of Parkinson’s Disease

Adcapone Tablet is a prescription medication used to manage the symptoms of Parkinson’s disease, particularly the “wearing-off” effects like stiffness, tremors, poor muscle control, and muscle spasms. It is typically prescribed alongside carbidopa/levodopa to enhance their effectiveness. This COMT inhibitor helps stabilize dopamine levels in the brain, improving motor function and coordination. It can be taken with or without food, but consistency in timing (preferably at bedtime) is crucial for optimal results. Always follow your doctor’s dosage instructions and avoid sudden discontinuation to prevent worsening symptoms.

Uses of Adcapone Tablet:

Treatment of Parkinson’s disease (wearing-off symptoms).

Benefits of Adcapone Tablet:

Improves muscle control, reduces tremors and stiffness, and prolongs the effectiveness of levodopa therapy.

Side Effects of Adcapone Tablet:

Common side effects include nausea, vomiting, fatigue, confusion, constipation, insomnia, nightmares, dizziness, diarrhea, and hallucinations. It may also cause urine discoloration (brownish-orange), which is harmless. Consult your doctor if side effects persist or worsen.

How to Use?

Take as prescribed, usually with levodopa/carbidopa. Swallow whole (do not crush/chew) with water, with or without food, at a fixed time daily.

How the Tablet Works?

It inhibits the enzyme COMT, prolonging dopamine activity in the brain and improving motor function in Parkinson’s patients.

Safety Advice:

• Alcohol: Unsafe – May cause excessive drowsiness.
• Pregnancy: Consult doctor – Potential risks to the fetus.
• Breastfeeding: Unsafe – May pass into breast milk.
• Driving: Caution – May cause dizziness or low blood pressure.
• Kidney: Likely safe (dose adjustment may not be needed).
• Liver: Unsafe – Avoid use in liver disease.

What If You Missed a Dose?

Skip the missed dose and resume your schedule. Do not double the dose.

FAQs:

Q1. Can Adcapone Tablet be crushed or split?

No. Swallow it whole with water at the same time as your levodopa dose.

Q2. Does this tablet change urine color?

Yes, it may turn urine brownish-orange. This is harmless and temporary.

Q3. Will it make me sleepy?

It may cause daytime sleepiness. Avoid driving if drowsiness occurs.

Q4. What is impulse control disorder with Adcapone Tablet?

Rare urges (gambling, overeating, hyper-sexuality) may occur. Report to your doctor immediately.

Q5. What if I overdose on Adcapone Tablet?

Seek emergency help if you experience confusion, extreme drowsiness, or skin discoloration.

Q6. Does Adcapone Tablet cross the blood-brain barrier?

No. It works peripherally to prolong levodopa’s effects.

Q7. Does Adcapone Tablet affect fertility?

No evidence, but avoid during pregnancy/breastfeeding.