Gestone Injection (Progesterone) – Fertility Support & Hormone Therapy

Gestone Injection provides natural progesterone, a crucial hormone for female reproductive health. This intramuscular injection is prescribed for fertility treatments, menstrual disorders, and hormone replacement therapy (HRT). Administered by healthcare professionals, it helps prepare the uterus for pregnancy, maintains early gestation, and prevents endometrial hyperplasia when used with estrogen. The injection form ensures direct hormone delivery for patients requiring immediate therapeutic effects or those with absorption issues.

Uses of Gestone Injection:

• Treatment of female infertility and menstrual irregularities
• Support for early pregnancy maintenance
• Prevention of premature labor
• Component of hormone replacement therapy (with estrogen)
• Management of dysfunctional uterine bleeding

Benefits of Gestone Injection:

• Direct delivery for faster therapeutic action than oral forms
• Promotes endometrial thickening for embryo implantation
• Helps maintain healthy pregnancy in high-risk cases
• Regulates menstrual cycles in hormonal imbalances
• Reduces risk of endometrial abnormalities during HRT

Side Effects of Gestone Injection:

Common side effects:

• Injection site reactions (pain, swelling)
• Headache, dizziness, fatigue
• Breast tenderness, vaginal discharge
• Mood changes, decreased libido
• Mild abdominal discomfort/bloating

Serious side effects (seek immediate help):

• Severe allergic reactions (rash, swelling)
• Sudden severe headache/vision changes
• Unusual vaginal bleeding
• Signs of blood clots (leg pain, chest discomfort)

How to Use Gestone Injection?

• Administered only by healthcare professionals (IM injection)
• Typical dosage: 50-100mg daily or as prescribed
• Rotate injection sites (upper outer quadrant of buttocks)
• Continue treatment as directed, even after pregnancy confirmation
• Never self-administer – requires proper injection technique

How Gestone Injection Works?

It provides bioidentical progesterone that:

• Transforms endometrium to support embryo implantation
• Maintains uterine quiescence to prevent early contractions
• Suppresses gonadotropins to prevent new follicular development
• Balances estrogen effects to prevent endometrial hyperplasia
• Supports early placental development in pregnancy

Safety Advice:

• Pregnancy: Used only under strict medical supervision
• Breastfeeding: Consult doctor – limited safety data
• Driving: May cause dizziness – avoid if affected
• Medical History: Inform doctor about breast cancer, liver disease, or blood clot history
• Drug Interactions: Avoid with tamoxifen, aromatase inhibitors, HIV medications

What If You Miss a Dose?

Contact your healthcare provider immediately to reschedule. Never attempt self-injection.

FAQs:

Q1. How often are Gestone Injections given during pregnancy?

Frequency varies (typically 1-3 times weekly) based on your condition. Your doctor will create a personalized schedule.

Q2. Why must injections be given by a healthcare provider?

Progesterone injections require precise intramuscular technique and sterile handling to prevent complications like abscesses or nerve damage.

Q3. Can Gestone Injection cause permanent weight gain?

Any weight changes are usually temporary fluid retention, not fat accumulation. Normalizes after treatment ends.

Q4. How quickly does it work for irregular periods?

Menstrual cycles typically regulate within 1-2 months of consistent therapy.

Q5. What’s the difference between injection and oral progesterone?

Injections bypass first-pass metabolism, providing more consistent hormone levels – ideal for patients with absorption issues or needing rapid effects.

Q6. Are there alternatives if I can’t tolerate injections?

Yes – vaginal suppositories or oral micronized progesterone may be options. Discuss with your doctor.