Lefumide 10 Tablet (Leflunomide) – Treatment for Rheumatoid & Psoriatic Arthritis

Lefumide 10 Tablet is a disease-modifying anti-rheumatic drug (DMARD) used to treat rheumatoid arthritis and psoriatic arthritis. This lower-dose formulation helps slow disease progression while effectively reducing joint pain, swelling, and stiffness. The tablet works by targeting the underlying autoimmune response that causes joint inflammation. Patients can take Lefumide Tablet with or without food, but consistency in timing is crucial for optimal results. While generally well-tolerated, some patients may experience mild side effects like nausea or headache. Regular liver function tests are recommended as this medication may affect liver enzymes. Always complete the full course as prescribed, even if symptoms improve.

Uses of Lefumide 10 Tablet:

• Rheumatoid Arthritis: Reduces joint inflammation and prevents deformity
• Psoriatic Arthritis: Manages joint symptoms associated with psoriasis

Benefits of Lefumide 10 Tablet:

In Autoimmune Arthritis: It provides dual action – it not only relieves painful symptoms but actually slows the progression of joint damage. For psoriatic arthritis patients, it helps control both skin lesions and joint inflammation, improving overall mobility and quality of life. The 10mg dose offers effective treatment with potentially fewer side effects than higher doses.

Side Effects of Lefumide 10 Tablet:

Most side effects are mild but consult your doctor if persistent:

• Nausea and vomiting
• Headache
• Skin rash
• Diarrhea
• Elevated liver enzymes
• Indigestion
• Dizziness
• Reduced appetite
• Temporary hair thinning
• Mild weight loss
• Respiratory infections

How to Use Lefumide 10 Tablet?

Swallow the tablet whole with water, with or without food. Take at the same time daily for consistent blood levels. Do not crush or chew. Your doctor may start with a higher loading dose before reducing to maintenance therapy.

How Lefumide 10 Tablet Works?

The tablet contains leflunomide which inhibits dihydroorotate dehydrogenase, an enzyme crucial for immune cell proliferation. This action reduces the overactive immune response causing joint inflammation in autoimmune arthritis, providing both symptomatic relief and disease modification.

Safety Advice:

• Alcohol: UNSAFE – Increases risk of liver damage
• Pregnancy: UNSAFE – Strictly contraindicated
• Breastfeeding: CONSULT DOCTOR – Potential risk to infant
• Driving: CAUTION – May cause dizziness
• Kidney Disease: MONITOR – Dose adjustment may be needed
• Liver Disease: AVOID – High risk of complications

What If You Miss a Dose?

Take the missed dose as soon as remembered. If near the next dose time, skip the missed one. Never take double doses. Consistent dosing is important for effectiveness.

FAQs:

Q1. Is weight loss common with Lefumide 10 Tablet?

Mild weight loss may occur due to reduced appetite, but significant weight changes should be reported to your doctor.

Q2. When should I seek immediate medical attention?

Contact your doctor immediately for: yellowing skin/eyes, unusual bleeding/bruising, persistent fever, severe skin reactions, or breathing difficulties.

Q3. How soon can I conceive after stopping treatment?

Wait at least 2 years or undergo drug elimination procedure. Leflunomide remains in the body for extended periods.

Q4. When will I notice improvement in symptoms?

Initial relief may take 4-8 weeks. Maximum benefits typically appear after 4-6 months of continuous therapy.

Q5. Does this medication increase cancer risk?

There’s minimal risk of lymphoproliferative disorders with long-term use. Regular monitoring helps detect any abnormalities early.

Q6. Can I take vaccines while on this medication?

Live vaccines (like shingles vaccine) must be avoided. Consult your doctor before any vaccinations.