Lioresal 10 Tablet – Central Muscle Relaxant for Neurological Spasticity

Lioresal 10 Tablet is a higher-strength oral muscle relaxant primarily used to manage symptoms of muscle spasticity such as stiffness, rigidity, and tightness. It is commonly prescribed in neurological conditions including cerebral palsy, multiple sclerosis, motor neuron disease, and traumatic brain or spinal cord injury.

Uses of Lioresal 10 Tablet:

• Muscle spasticity due to neurological disorders

Benefits of Lioresal 10 Tablet:

Lioresal 10 works by acting on specific receptors in the spinal cord to reduce excessive muscle tone and involuntary muscle contractions. It blocks neurotransmitters responsible for sending overactive signals to muscles, resulting in relief from stiffness and pain. This improves mobility, coordination, and overall quality of life in affected individuals.

Mechanism of Action

Lioresal contains Baclofen, a GABA-B receptor agonist. It decreases nerve transmission in the spinal cord, reducing excitatory neurotransmission and muscle spasticity without weakening voluntary muscle strength.

Dosage and Administration:

• Take the medicine as prescribed by your doctor.
• Swallow whole with a glass of water; do not chew or crush.
• Take it with food or milk to reduce gastrointestinal discomfort.
• For night cramps or stiffness, the dose can be adjusted to bedtime or 1 hour before activity like physiotherapy or bathing.

Side Effects:

Most side effects are mild and transient. However, consult your physician if they persist or worsen.

• Drowsiness
• Dizziness
• Fatigue
• Weakness
• Nausea
• Headache
• Constipation
• Convulsions
• Hypotension (low BP)
• Hypotonia (decreased muscle tone)
• Urinary retention
• Agitation
• Chills
• Increased WBC count

Precautions & Safety Advice:

• Alcohol: UNSAFE – Increases risk of sedation, dizziness, and impaired motor function.
• Pregnancy: CONSULT YOUR DOCTOR – Not recommended unless clearly needed. Animal studies show risk.
• Breastfeeding: SAFE IF PRESCRIBED – Minimal transfer into milk; generally considered safe.
• Driving/Operating Machines: UNSAFE – Can impair alertness and coordination due to drowsiness and dizziness.
• Kidney Impairment: USE WITH CAUTION – Dosage adjustment required. Risk of urinary issues.
• Liver Impairment: USE WITH CAUTION – May increase liver enzymes; regular monitoring required.

Missed Dose?

If you forget to take Lioresal 10 Tablet, take it as soon as you remember. If it’s near your next dose, skip the missed one. Do not double the dose.

Drug Interactions:

Concurrent use with the following medicines may enhance side effects or alter therapeutic action. Monitor closely and inform your physician.

Drug	Interaction Effect
Trihexyphenidyl	Dry mouth, blurred vision, urinary retention, constipation, confusion
Tramadol	Increased sedation, risk of respiratory depression
Alfuzosin / Amlodipine / Atenolol	May lead to hypotension, dizziness, cold skin, shallow breathing

FAQs:

Can Lioresal 10 Tablet cause sleepiness?

Yes. Sleepiness, dizziness, and vision issues are common. Avoid driving or using machinery unless you know how the medicine affects you.

Is Lioresal 10 Tablet used for anxiety?

It is not approved for anxiety treatment, but it may reduce trauma-related stress in some off-label cases.

Can I take Lioresal 10 Tablet if I have liver problems?

Use with caution. It may raise liver enzyme levels. Liver function tests should be done regularly.

Is Lioresal 10 Tablet harmful to kidneys?

It may cause urinary problems even in patients with normal kidneys. Dose adjustments are necessary in renal impairment or dialysis.

How should Lioresal 10 be taken for best results?

Take with food or milk if you feel nauseous. Use it at night if treating nighttime spasms. Follow doctor’s instructions strictly.