Loxof 250mg Tablet (Levofloxacin) – Broad-Spectrum Antibiotic

Loxof 250mg Tablet contains Levofloxacin, a fluoroquinolone antibiotic used to treat a wide range of bacterial infections. It is commonly prescribed for infections of the urinary tract, respiratory tract (e.g., pneumonia), nose, throat, skin, and soft tissues. It works by inhibiting bacterial enzymes (DNA-gyrase and topoisomerase IV), essential for bacterial DNA replication, transcription, repair, and recombination—thereby stopping bacterial growth and eliminating the infection.

Uses of Loxof 250mg Tablet:

• Treatment of Bacterial infections
• Urinary tract infections (UTIs)
• Respiratory tract infections (e.g., pneumonia, bronchitis)
• Ear, nose, and throat infections
• Skin and soft tissue infections

Benefits of Loxof 250mg Tablet:

• Rapid relief from bacterial symptoms like fever, inflammation, and pain
• Broad-spectrum activity against gram-positive and gram-negative bacteria
• Effective in treating multi-organ infections with a single drug
• Improves patient compliance with once or twice daily dosing

Side Effects of Loxof 250mg Tablet:

Common side effects (usually temporary):

• Headache
• Dizziness
• Nausea
• Constipation
• Diarrhea (may subside after treatment ends)

Note: Consult your doctor if diarrhea is severe, persistent, or contains blood.

How to Use Loxof 250mg Tablet?

• Swallow the tablet whole with water. Do not chew, crush, or break.
• Can be taken with or without food.
• Take at the same time daily for best results.
• Avoid dairy products (milk, paneer, cheese, curd, butter, ice cream) at the time of taking the medicine.

How Loxof 250mg Tablet Works?

Loxof 250mg Tablet contains Levofloxacin, which works by inhibiting the action of bacterial enzymes DNA-gyrase and topoisomerase IV. These enzymes are vital for DNA replication and repair. Inhibition of these enzymes prevents bacterial multiplication and leads to bacterial death.

Safety Advice:

• Alcohol: Safe. No known harmful interaction with alcohol.
• Pregnancy: Unsafe. May harm the unborn baby. Use only in life-threatening situations as prescribed.
• Breastfeeding: Probably unsafe. Drug may pass into breastmilk and harm the baby.
• Driving: Unsafe. May cause dizziness, drowsiness, or blurred vision. Avoid driving if affected.
• Kidney: Use with caution. Dose adjustment may be necessary in kidney impairment. Consult doctor.
• Liver: Limited data. Use with caution. Discontinue and seek medical advice if jaundice develops.

Missed Dose?

If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose. Do not double the dose to make up for it.

Drug Interactions:

Potentially serious drug interactions include:

• Domperidone: Life-threatening interaction; may cause fatal heart rhythm disorders.
• Artemether (oral/injection): Severe risk of heart rhythm disturbances, especially in elderly or cardiac patients. ECG monitoring may be required.
• Amiodarone (oral/injection): Serious risk of QT prolongation and arrhythmia. ECG monitoring advised.

FAQs:

Is Loxof 250mg Tablet safe?

Yes, it is safe when taken as prescribed. Follow the doctor’s dosage and duration instructions. Report any unusual symptoms promptly.

Can I stop taking Loxof when I feel better?

No. Complete the full course to avoid reinfection or bacterial resistance. Stopping early may cause symptoms to return or worsen.

Does Loxof 250mg Tablet cause diarrhea?

Yes. It may disrupt beneficial gut bacteria. Mild diarrhea is common and temporary. Consult a doctor for severe or bloody diarrhea.

Can Loxof cause muscle damage?

Yes, especially in people over 60 years old. Inform your doctor immediately if you experience muscle pain or weakness, especially in the ankle (tendonitis or tendon rupture).

What precautions should I take while using Loxof?

• Avoid sunlight and use sunscreen due to possible photosensitivity.
• Do not take dairy products simultaneously with the tablet.
• Do not drive if feeling dizzy or visually impaired.