Loxof 750mg Tablet (Levofloxacin) – Broad-Spectrum Antibiotic

Loxof 750mg Tablet contains Levofloxacin, a powerful fluoroquinolone antibiotic used to treat various bacterial infections. It is highly effective against infections of the urinary tract, respiratory tract (including pneumonia), skin, nose, and throat. Loxof 750mg works by inhibiting bacterial DNA-gyrase, stopping bacterial multiplication and repair, effectively eliminating the infection.

Uses of Loxof 750mg Tablet:

• Bacterial infections
• Urinary Tract Infections (UTIs)
• Lung infections including pneumonia
• Throat and sinus infections
• Skin and soft tissue infections

Benefits of Loxof 750mg Tablet:

• Broad-spectrum action against gram-positive and gram-negative bacteria
• Effective treatment of complex or resistant infections
• Once-daily dosing improves compliance
• Rapid symptom relief when taken correctly

Dosage & Administration:

• Take as prescribed by your doctor.
• Swallow the tablet whole with water. Do not chew or crush.
• Can be taken with or without food. However, maintain a consistent time each day.
• Avoid dairy products (milk, curd, paneer, cheese, butter, ice cream) during the dosing time as they interfere with absorption.
• Complete the full course even if symptoms improve early.

Missed Dose?

If you miss a dose, take it as soon as you remember. If it’s close to the time of the next dose, skip the missed dose. Do not double the dose to make up.

Mechanism of Action:

Loxof 750mg inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and repair in bacteria. Blocking them results in bacterial cell death.

Common Side Effects of Loxof 750mg Tablet:

• Headache
• Dizziness
• Nausea
• Constipation
• Diarrhea (usually mild and self-limiting)

Note: If you notice blood in stools or persistent diarrhea, consult your doctor immediately.

Precautions & Warnings:

• Allergy: Avoid if allergic to Levofloxacin or any other quinolone antibiotics.
• Kidney Disease: Use with caution. Dose adjustment may be necessary.
• Liver Disease: Limited data. Discontinue if jaundice appears and consult a doctor.

Specific Warnings

• Alcohol: Safe. No harmful interaction known.
• Pregnancy: Unsafe. Avoid during pregnancy unless absolutely necessary and prescribed.
• Breastfeeding: Possibly unsafe. May pass into breast milk and harm the baby.
• Driving: Unsafe. May cause dizziness or drowsiness. Avoid operating heavy machinery.

Drug Interactions:

Avoid combining Loxof 750mg Tablet with:

• Domperidone: Life-threatening interaction. May cause fatal arrhythmia.
• Artemether (Oral/Injection): High risk of QT interval prolongation. ECG monitoring recommended in elderly or cardiac patients.
• Amiodarone (Oral/Injection): May cause serious heart rhythm disorders, especially in those with heart conditions or low potassium levels.

Frequently Asked Questions (FAQs):

Is Loxof 750mg Tablet safe?

Yes, it is safe when used exactly as prescribed by your doctor. Do not skip doses or exceed recommended duration.

Can I stop taking Loxof 750mg once I feel better?

No. Complete the full prescribed course even if you feel better to ensure complete eradication of bacteria and to prevent resistance.

Can Loxof 750mg cause diarrhea?

Yes. It affects both harmful and beneficial gut bacteria. If diarrhea is severe or bloody, contact your doctor immediately.

Does Loxof 750mg increase risk of muscle damage?

Yes. It can cause muscle or tendon damage, particularly in the elderly. The Achilles tendon is commonly affected. Report any joint or muscle pain to your doctor.

What if I miss a dose?

Take it as soon as remembered. If it’s almost time for the next dose, skip the missed dose. Do not double dose.