Pentasa Granules (Mesalazine) – Treatment for Ulcerative Colitis & Crohn’s Disease

Pentasa Granules contain Mesalazine (5-ASA), an anti-inflammatory medication specifically formulated to treat ulcerative colitis and Crohn’s ileocolitis. These oral granules work throughout the bowel to reduce inflammation, effectively alleviating symptoms like diarrhea, rectal bleeding, and abdominal pain. The unique formulation releases mesalazine gradually along the gastrointestinal tract, providing targeted relief. For optimal results, take as directed with food at consistent times daily. Complete the full prescribed course to prevent symptom recurrence and maintain remission.

Uses of Pentasa Granules:

– Active ulcerative colitis (mild to moderate)
– Crohn’s ileocolitis
– Maintenance of remission in inflammatory bowel disease

Benefits of Pentasa Granules:

– Targeted release: Acts throughout entire gastrointestinal tract
– Symptom control: Reduces diarrhea, bleeding and abdominal pain
– Maintenance therapy: Helps prevent disease flare-ups
– Convenient administration: Granules can be mixed with water/milk

Side Effects of Pentasa Granules:

Common temporary side effects may include:
– Nausea/vomiting
– Abdominal pain/flatulence
– Diarrhea
– Headache/rash

Serious allergic reactions (rare): facial swelling, unusual bleeding, fever – seek immediate medical help if these occur

How to Use Pentasa Granules?

1. Mix contents of sachet in glass of water/milk
2. Stir well and drink immediately
3. Can be taken with or without food
4. Maintain consistent dosing times
5. Continue full course as prescribed
6. Do not chew or crush granules

How Pentasa Granules Work?

It contain Mesalazine which:
– Reduces intestinal inflammation throughout GI tract
– Blocks prostaglandins (inflammatory chemicals)
– Promotes mucosal healing
– Prevents disease flare-ups when used long-term

Safety Advice:

Alcohol: May worsen colitis symptoms (consult doctor)
Pregnancy: Potential risk – medical supervision required
Breastfeeding: Not recommended
Kidney Disease: Requires dose adjustment (avoid in severe cases)
Liver Disease: Caution needed – monitor liver function
Drug Interactions: Azathioprine, mercaptopurine, clozapine

What If You Miss a Dose?

Take as soon as remembered unless close to next dose time. Never double the dose to compensate.

FAQs:

Q1. Can I stop Pentasa when symptoms improve?

No – continue full prescribed course to maintain remission. Sudden stoppage may trigger relapse.

Q2. Is alcohol permitted with Pentasa Granules?

Alcohol may irritate bowel – best avoided during active colitis treatment.

Q3. Does Pentasa cause joint pain?

Joint pain is a possible side effect – inform your doctor if persistent.

Q4. What’s the best time to take Pentasa Granules?

Take at consistent time daily, with or without food as directed.

Q5. How should I prepare the granules?

Mix entire sachet contents in water/milk, stir and drink immediately.

Q6. Can I take Pentasa with other IBD medications?

Consult doctor before combining with immunosuppressants like azathioprine.

Q7. What if I experience severe side effects?

Seek immediate medical help for allergic reactions or unusual bleeding.