Pletoz 50 Tablet – Uses, Benefits, Side Effects & FAQs

Pletoz 50 Tablet is a prescription medicine used to treat pain in the legs caused by intermittent claudication — a condition due to poor blood circulation. It helps relieve symptoms like cramping, numbness, or weakness while walking by improving blood flow to the affected areas.

Uses of Pletoz 50 Tablet:

• Treatment of Intermittent Claudication
• Peripheral Vascular Disease

Benefits of Pletoz 50 Tablet:

Pletoz 50 Tablet works by widening blood vessels and reducing the stickiness of platelets, thus enhancing blood circulation, especially to the lower limbs. This helps alleviate the leg pain and fatigue experienced during walking or physical activity. Regular use of this medicine can result in better mobility and improved quality of life for patients suffering from intermittent claudication.

How to Use Pletoz 50 Tablet?

• Take the Tablet exactly as prescribed by your doctor.
• It should be swallowed whole without chewing or crushing.
• Take it on an empty stomach at the same time every day for best results.

How Pletoz 50 Tablet Works?

It contains cilostazol, a phosphodiesterase III inhibitor. It works by dilating the blood vessels and preventing platelets from sticking together, which in turn enhances blood flow to the legs and helps reduce symptoms of intermittent claudication.

Side Effects of Pletoz 50 Tablet:

Most side effects of Pletoz 50 Tablet are mild and resolve on their own. However, consult your doctor if they persist or become severe.

• Headache
• Palpitations
• Dizziness
• Abnormal stools
• Diarrhea
• Edema (swelling)
• Abdominal pain
• Inflammation of the nose
• Increased heart rate
• Bleeding disorder

Safety Advice:

Alcohol

Consult your doctor before consuming alcohol with the Tablet, as its interaction is not clearly known.

Pregnancy

It may be unsafe during pregnancy. Consult your doctor to understand the risks and benefits before use.

Breastfeeding

It is probably unsafe during breastfeeding. It may pass into breastmilk and harm the baby. Always consult your doctor.

Driving

It may cause dizziness or drowsiness. Avoid driving or operating machinery if you experience such symptoms.

Kidney

This medicine is generally safe for patients with kidney disease. No dose adjustment is typically required.

Liver

It can be used in patients with liver disease. However, consult your doctor in cases of moderate to severe liver impairment.

Drug Interactions:

• Pimozide (Oral Route): Avoid concurrent use. It may increase blood levels of pimozide, leading to severe side effects.
• Urokinase (Injection Route): May increase bleeding risk. Monitor for signs of unusual bleeding.
• Streptokinase (Injection Route): Increases bleeding risk. Notify your doctor if signs appear.
• Fondaparinux (Injection Route): High bleeding risk. Use only if absolutely necessary under supervision.
• Bemiparin (Injection Route): May increase bleeding risk. Avoid unless essential and monitor closely.

Missed Dose?

If you forget to take a dose of the Tablet, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double the dose to make up for the missed one.

FAQs:

Q1: Can the use of Pletoz 50 Tablet increase the risk of bleeding?

Yes, It may increase the risk of bleeding. Be cautious during activities that may cause injuries and consult your doctor if you notice abnormal bleeding or bruises.

Q2: When will I feel better after taking Pletoz 50 Tablet?

You may start to notice improvements within 2-4 weeks, but full benefits may take up to 12 weeks. Continue taking it as prescribed.

Q3: For how long should I take Pletoz 50 Tablet?

Your doctor will assess your progress after 3 months. Continue using it as directed unless advised otherwise by your doctor.

Q4: Should Pletoz 50 Tablet be stopped before surgery?

Yes, stop taking the Tablet at least 5 days prior to any planned surgery due to the increased risk of bleeding.

Q5: Why is Pletoz 50 Tablet harmful for heart failure patients?

It is not recommended in any stage of heart failure as it may worsen the condition and reduce lifespan in such patients.

Q6: Does Pletoz 50 Tablet raise or lower blood pressure?

It usually lowers blood pressure by dilating blood vessels, but in rare cases, it may also increase it. Monitor your blood pressure regularly.